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Fifty years ago, his LOVE painting made Robert Indiana a worldwide sensation. But for the artist, the work also had an intensely personal meaning.

New findings about the health effects of e-cigarettes add to a small but growing body of research that undercuts the widely presumed safety of the alternative to conventional cigarettes.

The 13-year-old died two days after he was physically restrained by a staff member at a private school that provides special education services to students in California.

Legal battles and local tensions persist two years after the North Dakota prairie was filled with thousands of indigenous and environmental protesters opposed to the Dakota Access Pipeline.

India's economy is growing, but job creation has not kept pace. Unemployment is at a four-decade high. Hardest hit are educated millennials, whose ambitions are bigger than those of their parents.

The EPA says it will keep limits on toxic mercury emissions from coal plants but now deems them not cost-effective. Environmental groups worry the move could hinder future regulations.

On the day after Thanksgiving, holiday shoppers are looking for bargains. Online is the fastest growing type of shopping, but brick-and-mortar stores still dominate for holiday sales

During a Senate Finance Committee hearing about the Republicans' last-ditch effort to repeal the Affordable Care Act, it became clear the legislation would not have the votes to pass.

The launch comes just weeks after Pyongyang tested its first intercontinental ballistic missile. The Pentagon says the missile, which landed in the Sea of Japan, was no threat to the U.S.

The opioid epidemic caused U.S. life expectancy to fall for the second year in a row, marking the first time that has happened since the early 1960s. Death rates also continued to rise.