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NPR is pulling together some of its favorite stories from 2022 that may have been easy to miss among the year's major news but hard to forget. Thursday, NPR shares its favorite musical moments.

A Mississippi woman's life has been transformed by a treatment for sickle cell disease with the gene-editing technique CRISPR. All her symptoms from a disease once thought incurable have disappeared.

A fundraiser for the pro-Bush superPAC Right to Rise USA blasted the campaign strategy in an NPR interview. Now, he's accused of having an ax to grind against Bush's campaign manager.

NPR's Steve Inskeep asks U.S. Senator Rick Scott of Florida, chair of the National Republican Senatorial Committee, for the GOP's closing argument to voters ahead of the midterm elections.

In his new book Of Boys and Men, Richard V. Reeves of the Brookings Institution argues that men must move into fields that are now dominated by women to reverse economic declines.

Latino voters wield a lot power in the swing state of Nevada, where the midterm elections could determine which party controls Congress in the new year.

In Montana and across the nation, homeless shelters report the worrisome trend that seniors are a growing proportion of their residents.

NPR's Eric Deggans talks with director Ryan Coogler about his latest film, Black Panther: Wakanda Forever.

NPR's Mary Louise Kelly talks with actress Sharon Horgan about her TV show "Bad Sisters" and its season finale. It's about sisters who dispose of one of their husbands — then things get complicated.

Nearly three years into the pandemic, travel has returned but hotel staff have not. Unable to find workers, hotel owners and managers are having to adapt to what they believe is the new normal.